SimpleBox is lightweight, library-independent, cross browser lightbox script(Version 1.0 - released August 31st, 2008)
More projects from Fotis Evangelou
(images taken from Flickr via JSON)
To use SimpleBox, you just grab the simplebox.js, simplebox.css & simplebox_ie6.css files, attach them to your page and then simply add rel="simplebox" in links pointing to image files. See the source code of this page for more.